Vardenafil hydrochloride Good Manufacturer supply High Quality 224785-91-5
- Molecular Formula:C23H33ClN6O4S
- Molecular Weight:525.06
- Appearance/Colour:White to off-white cyrstalline solid
- Vapor Pressure:5.17E-19mmHg at 25°C
- Melting Point:214-216 °C
- Boiling Point:692.2 °C at 760 mmHg
- Flash Point:372.5 °C
- PSA：121.28000
- LogP:3.82900
Vardenafil hydrochloride (224785-91-5) Usage
Vardenafil was the second agent to be marketed and had the advantage that its onset time was not reduced by taking the medication on a full stomach . It is 30 times more potent as an inhibitor of PDE5 (mean IC50, 3.9 nM) than sildenafil and 10 times more potent than tadalafil, with a greater selectivity (>1,000 times) for human PDE5 than for human PDE2, PDE3, and PDE4 and moderate selectivity (>80 times) for PDE1. The PDE inhibitory selectivity and both the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil. Vardenafil specifically inhibited the hydrolysis of cGMP by PDE5, with an IC50 of 0.7 nM (sildenafil 6.6 nM). The IC50 of vardenafil for PDE1 was 180 nM, for PDE6 11 nM, and for PDE2, PDE3 and PDE4 more than 1,000 nM.
How to get the best price on Vardenafil hydrochloride?
Zibo Hangyu Biotechnology Development Co., Ltd is a quality supplier and manufacturer of Vardenafil hydrochloride . You can buy high quality, low price Vardenafil hydrochloride 224785-91-5 here.
Zibo Hangyu Biotechnology Development Co., Ltd. is a comprehensive chemical enterprise focusing on fine chemical products and pharmaceutical intermediates, integrating research and development, production and sales. The company is equipped with advanced equipment quality inspection and research center. At the same time, the company has excellent talents with rich experience in process development and quality control. To provide customers with total solutions from raw material processing to chemical synthesis systems. The company has established a standardized and perfect quality standard system to provide stable and high quality production and service.
Milestones
- 2012yearThe company was founded, began to engage in the production and supply of chemical raw materials
- 2014yearExpand the scale of production, pharmaceutical raw materials production workshop was established
- 2016yearCooperated with domestic and foreign chemical platforms to promote self-produced and high-end pharmaceutical intermediates
- 2019yearIn recent years to participate in the international pharmaceutical raw materials exhibitions
- 2023yearBusiness continues to expand, Production and Sales teams continue to grow
- 2026yearPlans to set up foreign branches
