Zileuton Good Manufacturer supply High Quality 111406-87-2
- Molecular Formula:C11H12N2O2S
- Molecular Weight:236.294
- Appearance/Colour:crystalline solid
- Vapor Pressure:7.29E-09mmHg at 25°C
- Melting Point:157-158 °C
- Refractive Index:1.704
- Boiling Point:449.4 °C at 760 mmHg
- PKA:pKa 10.3(H2O t undefined I undefined) (Uncertain)
- Flash Point:225.6 °C
- PSA：94.80000
- Density:1.401 g/cm3
- LogP:3.43250
Zileuton (111406-87-2) Usage
Zyflo was launched in the US for chronic asthma. It can be prepared in three steps from 2-acetylbenzo[b]thiophene. Zyflo is a reversible direct inhibitor of 5- lipoxgenase that is orally-active. It was able to effect a 70-100 YO reduction in LTB4, LTE4, LTD4 and LTC4. Zyflo has no effect on myeloperoxidase activity, neutrophil degranulation, mast cell histamine release or phospholipase A2 activities. It did not inhibit cyclooxygenase as witnessed by the formation of TXB2. It significantly attentuated asthmatic response to cold dry air, inhibited exercise-induce bronchoconstriction, and attenuated induced bronchospasms. Zyflo has antiinflammatory effects as witnessed by a decrease in edema, mucus production and cellular infiltration. It had a bronchodilatory effect within 2 h and increased spirometry results by 18%.
How to get the best price on Zileuton?
Zibo Hangyu Biotechnology Development Co., Ltd is a quality supplier and manufacturer of Zileuton . You can buy high quality, low price Zileuton 111406-87-2 here.
Zibo Hangyu Biotechnology Development Co., Ltd. is a comprehensive chemical enterprise focusing on fine chemical products and pharmaceutical intermediates, integrating research and development, production and sales. The company is equipped with advanced equipment quality inspection and research center. At the same time, the company has excellent talents with rich experience in process development and quality control. To provide customers with total solutions from raw material processing to chemical synthesis systems. The company has established a standardized and perfect quality standard system to provide stable and high quality production and service.
Milestones
- 2012yearThe company was founded, began to engage in the production and supply of chemical raw materials
- 2014yearExpand the scale of production, pharmaceutical raw materials production workshop was established
- 2016yearCooperated with domestic and foreign chemical platforms to promote self-produced and high-end pharmaceutical intermediates
- 2019yearIn recent years to participate in the international pharmaceutical raw materials exhibitions
- 2023yearBusiness continues to expand, Production and Sales teams continue to grow
- 2026yearPlans to set up foreign branches
