Tofacitinib citrate Good Manufacturer supply High Quality 540737-29-9
- Molecular Formula:C16H20N6O·C6H8O7
- Molecular Weight:504.50
- Melting Point:201 °C (decomp)
- Boiling Point:585.8 °C at 760 mmHg
- Flash Point:308.1 °C
- PSA：221.04000
- LogP:0.23418
Tofacitinib citrate (540737-29-9) Usage
Tofacitinib citrate is a king of drugs developed by the US pharmaceutical company Pfizer for treating rheumatoid arthritis, trade name Xeljanz, for the treatment of methotrexate inadequate response or intolerance to severe active rheumatoid arthritis (RA) in adult patients. Tofacitinib citrate is an oral Janus kinase (JAK) inhibitor used to treat autoimmune diseases by modulating the immune response. It works by selectively inhibiting JAK enzymes, which are involved in the signaling pathways of various cytokines and growth factors that regulate immune and inflammatory responses. By blocking these pathways, tofacitinib reduces inflammation and helps manage conditions such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Its ability to suppress excessive immune activity makes it effective in controlling symptoms and preventing disease progression in patients with chronic inflammatory disorders. It is produced through a multi-step synthesis involving condensation, hydrogenation, resolution, and N-acylation reactions, culminating in the salification of tofacitinib with citric acid.
How to get the best price on Tofacitinib citrate?
Zibo Hangyu Biotechnology Development Co., Ltd is a quality supplier and manufacturer of Tofacitinib citrate . You can buy high quality, low price Tofacitinib citrate 540737-29-9 here.
Zibo Hangyu Biotechnology Development Co., Ltd. is a comprehensive chemical enterprise focusing on fine chemical products and pharmaceutical intermediates, integrating research and development, production and sales. The company is equipped with advanced equipment quality inspection and research center. At the same time, the company has excellent talents with rich experience in process development and quality control. To provide customers with total solutions from raw material processing to chemical synthesis systems. The company has established a standardized and perfect quality standard system to provide stable and high quality production and service.
Milestones
- 2012yearThe company was founded, began to engage in the production and supply of chemical raw materials
- 2014yearExpand the scale of production, pharmaceutical raw materials production workshop was established
- 2016yearCooperated with domestic and foreign chemical platforms to promote self-produced and high-end pharmaceutical intermediates
- 2019yearIn recent years to participate in the international pharmaceutical raw materials exhibitions
- 2023yearBusiness continues to expand, Production and Sales teams continue to grow
- 2026yearPlans to set up foreign branches
