What is the Ubidecarenone?

Ubidecarenone is yellow-orange crystalline powder, while it's Molecular Formula is C59H90O4. yellow-orange crystalline powder Coenzyme Q10 (CoQ10) is a naturally occurring quinone found throughout the body in cell membranes, primarily in mitochondrial membranes, with highest concentrations in the heart, lungs, liver, kidneys, spleen, pancreas, and adrenal glands. It is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. In its reduced form, CoQ10 acts as an antioxidant, preventing the formation of reactive oxygen species. CoQ10 deficiencies have been associated with heart failure, hypertension, parkinsonism, mitochondrial encephalomyopathies, and other chronic diseases.[Cayman Chemical]

What is the CAS number for Ubidecarenone?

The CAS number of Ubidecarenone is 303-98-0.

What is Ubidecarenone (303-98-0) used for?

Coenzyme Q10 (CoQ10) is a quinone that is found throughout the human body in cell membranes, primarily in mitochondrial membranes, with the highest levels in the heart, lungs, liver, kidneys, spleen, pancreas, and adrenal glands. It exists in three redox states: fully oxidized (CoQ10/ubiquinone), partially reduced (semiquinone or ubisemiquinone), and fully reduced (ubiquinol; ). CoQ10 acts as an electron shuttle in the electron transport chain via its reduction to ubiquinol between mitochondrial complexes I and II, also known as NADH dehydrogenase and succinate dehydrogenase, respectively, and mitochondrial complex III, also known as cytochrome bc1 complex. CoQ10 is also reduced to ubiquinol by ferroptosis suppressor protein 1 (FSP1) with NADPH as a cofactor, and ubiquinol traps lipid peroxyl radicals and inhibits lipid peroxidation helping to prevent ferroptosis. Mutations in genes encoding enzymes involved in CoQ10 biosynthesis lead to primary CoQ10 deficiency, which is characterized by encephalopathy, cerebellar ataxia, infantile multisystemic form, nephropathy, and isolated myopathy. Secondary CoQ10 deficiency, induced by non-genetic impaired CoQ10 biosynthesis, insufficient CoQ10 intake, or excessive CoQ10 utilization, has been observed in a variety of conditions, including ataxia-oculomotor-apraxia 1 (AOA1), mitochondrial diseases, and hypercholesteremia with statin therapy. Formulations containing CoQ10 have been used in the treatment of CoQ10 deficiency.InChI:InChI=1/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+

What is the Ubidecarenone?

Ubidecarenone is yellow-orange crystalline powder, while it's Molecular Formula is C59H90O4. yellow-orange crystalline powder Coenzyme Q10 (CoQ10) is a naturally occurring quinone found throughout the body in cell membranes, primarily in mitochondrial membranes, with highest concentrations in the heart, lungs, liver, kidneys, spleen, pancreas, and adrenal glands. It is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. In its reduced form, CoQ10 acts as an antioxidant, preventing the formation of reactive oxygen species. CoQ10 deficiencies have been associated with heart failure, hypertension, parkinsonism, mitochondrial encephalomyopathies, and other chronic diseases.[Cayman Chemical]

What is the CAS number for Ubidecarenone?

The CAS number of Ubidecarenone is 303-98-0.

What is Ubidecarenone (303-98-0) used for?

Coenzyme Q10 (CoQ10) is a quinone that is found throughout the human body in cell membranes, primarily in mitochondrial membranes, with the highest levels in the heart, lungs, liver, kidneys, spleen, pancreas, and adrenal glands. It exists in three redox states: fully oxidized (CoQ10/ubiquinone), partially reduced (semiquinone or ubisemiquinone), and fully reduced (ubiquinol; ). CoQ10 acts as an electron shuttle in the electron transport chain via its reduction to ubiquinol between mitochondrial complexes I and II, also known as NADH dehydrogenase and succinate dehydrogenase, respectively, and mitochondrial complex III, also known as cytochrome bc1 complex. CoQ10 is also reduced to ubiquinol by ferroptosis suppressor protein 1 (FSP1) with NADPH as a cofactor, and ubiquinol traps lipid peroxyl radicals and inhibits lipid peroxidation helping to prevent ferroptosis. Mutations in genes encoding enzymes involved in CoQ10 biosynthesis lead to primary CoQ10 deficiency, which is characterized by encephalopathy, cerebellar ataxia, infantile multisystemic form, nephropathy, and isolated myopathy. Secondary CoQ10 deficiency, induced by non-genetic impaired CoQ10 biosynthesis, insufficient CoQ10 intake, or excessive CoQ10 utilization, has been observed in a variety of conditions, including ataxia-oculomotor-apraxia 1 (AOA1), mitochondrial diseases, and hypercholesteremia with statin therapy. Formulations containing CoQ10 have been used in the treatment of CoQ10 deficiency.InChI:InChI=1/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+

Ubidecarenone Good Manufacturer supply High Quality 303-98-0

Molecular Formula:C59H90O4
Molecular Weight:863.361
Appearance/Colour:yellow-orange crystalline powder
Vapor Pressure:1.23E-30mmHg at 25°C
Melting Point:49-51 °C
Refractive Index:1.525
Boiling Point:869 °C at 760 mmHg
Flash Point:324.5 °C
PSA：52.60000
Density:0.97 g/cm³
LogP:17.85390

Ubidecarenone (303-98-0) Usage

Ubidecarenone, also known as Coenzyme Q10 or ubiquinone, plays a crucial role in cellular energy production by facilitating the creation of ATP, the primary energy currency of cells, and acts as a potent antioxidant, protecting cells from damage caused by free radicals. It is produced through three main methods: extraction from biological tissues, chemical synthesis, and microbial fermentation. Ubidecarenone (Coenzyme Q10) purification typically involves a combination of solvent extraction, crystallization, chromatography, and recrystallization to achieve high purity. Initially, crude Ubidecarenone is extracted from microbial fermentation or chemical synthesis using organic solvents such as hexane or ethanol. The extract undergoes liquid-liquid extraction and filtration to remove impurities. Chromatographic techniques, including silica gel column chromatography or high-performance liquid chromatography (HPLC), are then employed to further refine the compound by separating it from structurally similar impurities. Finally, recrystallization from solvents like ethanol or acetone ensures the removal of residual contaminants, yielding a highly pure Ubidecarenone suitable for pharmaceutical or dietary applications.

How to get the best price on Ubidecarenone?

Zibo Hangyu Biotechnology Development Co., Ltd is a quality supplier and manufacturer of Ubidecarenone . You can buy high quality, low price Ubidecarenone 303-98-0 here.

Zibo Hangyu Biotechnology Development Co., Ltd. is a comprehensive chemical enterprise focusing on fine chemical products and pharmaceutical intermediates, integrating research and development, production and sales. The company is equipped with advanced equipment quality inspection and research center. At the same time, the company has excellent talents with rich experience in process development and quality control. To provide customers with total solutions from raw material processing to chemical synthesis systems. The company has established a standardized and perfect quality standard system to provide stable and high quality production and service.

Milestones

2012yearThe company was founded, began to engage in the production and supply of chemical raw materials
2014yearExpand the scale of production, pharmaceutical raw materials production workshop was established
2016yearCooperated with domestic and foreign chemical platforms to promote self-produced and high-end pharmaceutical intermediates
2019yearIn recent years to participate in the international pharmaceutical raw materials exhibitions
2023yearBusiness continues to expand, Production and Sales teams continue to grow
2026yearPlans to set up foreign branches

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